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Ab2 Bio Xprt Equipment & Supplies
4 equipment items found
Manufactured by:AB2 Bio Ltd. based inLausanne, SWITZERLAND
Tadekinig alfa is a recombinant Interleukin-18 Binding Protein (r-hIL-18BP) with a high affinity for IL-18, a major inflammatory cytokine. In healthy people, there is a large excess of naturally occurring IL-18BP keeping levels of free IL-18 low. However, in patients with certain inflammatory diseases, the IL-18/IL-18BP balance is disrupted, resulting in high levels of free and active IL-18, ...
Manufactured by:AB2 Bio Ltd. based inLausanne, SWITZERLAND
People with HLH usually develop symptoms within the first months or years of life. Symptoms may include fever, enlarged liver or spleen, cytopenia (decreased number of blood cells), and neurological abnormalities. All forms of HLH, including cases treated adequately, may have a high mortality rate. The long-term outlook (prognosis) of familial forms without treatment is poor, with a median ...
Manufactured by:AB2 Bio Ltd. based inLausanne, SWITZERLAND
Macrophage Activation Syndrome. Macrophage Activation Sysdrome (MAS) is a very severe complication of rheumatic diseases. Mortality ranges between 10-30% for patients with MAS and there is no registered therapy. MAS occurs frequently in systemic Juvenile Idiopathic Arthritis (soJIA) and in Adult onset Still’s Disease (AOSD) patients. It is characterized by severe systemic inflammation with ...
Manufactured by:AB2 Bio Ltd. based inLausanne, SWITZERLAND
AB2 Bio has developed the first and proprietary assay detecting free IL-18 allowing the identification of clinical entities that are driven by free ...